Streptocide (sulfanilamide) is an antibacterial drug, the first representative of sulfanilamide drugs.
The drug is active against streptococci, pneumococci, gonococci and other bacteria. Since the accidental discovery of penicillin in 1929, the era of antibiotics has begun in medicine. Streptocide was discovered one of the first.
It is used in the treatment of infectious and inflammatory diseases triggered by bacteria susceptible to the drug. From the side effects of Streptocide should be distinguished dyspeptic symptoms (nausea, vomiting, diarrhea), disorders of the blood system, dermatological allergic reactions.
Antibacterial agent of a broad spectrum.
Terms of sale from pharmacies
Can be bought without a doctor's prescription.
How much is Streptocid in pharmacies? The average price is at the level of 65 rubles.
Composition and release form
Pharmacies can find ointment and powder. Such types of the drug as Streptocid White and Streptocid soluble liniment are also known. Streptocide tablets since 2008 in Russia is not available and is not for sale.
The active substance is sulfonamide. Ointment Streptocid also contains paraffin soft white as an additional component. The powder contains 0.5 mg sulfonamide.
The substance has antimicrobial effects, is active against gram-positive and negative cocci. Applying powder to damaged skin accelerates wound healing, helps erosions epithelize faster. The mechanism of action is based on the connection of compounds with para-aminobenzoic acid, which is necessary for the vital activity of bacteria.
Due to the similarity with this acid, sulfonamides penetrate into the protoplasm of bacteria, replace the substrate, block the enzyme system. There is a violation of metabolic processes, microbes cease to grow and multiply due to the lack of folic acid intake. Sulfanilamide is active, rapidly absorbed from the gastrointestinal tract. Maximum concentration reaches a couple of hours, showing up in the blood.
Four hours after taking Streptocid is found in cerebrospinal fluid, saliva, gastric juice, bile, urine. Part of the molecule under the action of enzymes becomes acetoform, which reduces the antimicrobial activity of the agent. This form is found in 10-20% concentration in the blood, in the urine - up to 50%. In eight hours, the kidneys excrete 50% of the drug.
Indications for use
The drug is used in the treatment of the following inflammatory diseases that are caused by microorganisms that are susceptible to the action of the drug:
- sore throats;
- infectious diseases of the mucous membranes and skin.
Also, this tool is used in the treatment of infected burns (I-IIst.), Purulent wounds and other purulent-inflammatory processes of the skin.
Streptocide tablets prescribed for infectious diseases of the skin, upper respiratory tract, respiratory and urinary tract infections, wound infections.
Appointment during pregnancy and lactation
In contraindications to the drug indicated that Streptocid during pregnancy and lactation is prohibited. The active substance of the drug quickly passes through the placental barrier and is found in the blood of the fetus. In addition, it can cause toxic effects.
When breastfeeding the drug can cause nuclear jaundice in infants.
Dosage and method of use
As indicated in the instructions for use Streptocide powder can be applied externally to the damaged surface of the skin or injected into deep wounds. Also in a mixture with Sulfathiazole, Benzylpenicillin and Ephedrine, Streptocid is used to draw in nose during an acute rhinitis.
Powder is applied to the damaged surface of the skin, that is, first a little powder is poured onto the gauze, after which the gauze of the wound is “powdered” with gauze. You can also gently pour the powder directly from the bag onto the surface of the wound. But you should try to evenly distribute the powder on the surface of the wound. After applying the powder on the damaged surface, you can cover it with a gauze cloth on top, dress it or leave it uncovered. For a single application on the wound take 2 - 5 g of powder, depending on the size of the damage.
The powder can be applied to the wound surface 3 to 4 times a day. In this case, the multiplicity of powder application is determined by the course of the infectious-inflammatory process. For example, if a wound is weeping, with abundant discharge, then its surface is powdered frequently, up to 4 times per day. If the wound is dry, then it can be treated with Streptocide powder only 1 - 2 times a day. In such a situation, it is recommended to apply Streptocide powder 1 time per day if the wound is closed with a bandage after that, and 2 times a day if the wound is left open.
If the wound is deep, then Streptocide powder is blown directly into it. At the same time for one injection take 5 - 15 g of powder, depending on the size of the wound. After injection of the powder, the wound is usually closed with a bandage. The powder is injected 1 to 4 times a day, depending on the degree of intensity of discharge from the wound, guided by the rule: the more wet the wound is, the more often it is necessary to blow powder into it. Powder is applied to the wounds until they begin to heal or until the release of pus or inflammatory fluid from the wound surface stops.
One of the effective tools in the fight against acne is Streptocide. It is a good antiseptic and destroys pathogens. For the treatment of skin rashes, streptocidal ointment is most often used. The drug in powder form is more suitable in the manufacture of lotions and masks. Before using the ointment, you must wash your face and rub it with calendula tincture.
Then apply ointment to each pimple (do it twice a day for 2 weeks). You can also use tablets: crush 20 pieces into powder and mix with aloe juice to a consistency of sour cream, add a few drops of iodine. Apply this mixture on acne overnight, and in the morning wash it off with plain water. If the use of Streptocide does not help, then it is necessary to consult a doctor to determine the cause of acne (this may be a hormonal surge, blockage of pores or a violation of the gastrointestinal tract).
When using the product, allergic reactions are possible, in addition, the following side effects are observed: headache, paresthesia, nausea, dyspepsia, agranulocytosis, cyanosis, dizziness, tachycardia, vomiting, leukopenia, crystalluria.
Tablets can also cause diarrhea, and in rare cases nephrotoxic reactions, thrombocytopenia, hypoprothrombinemia, eosinophilia, visual disturbances, peripheral neuritis, hypothyroidism, ataxia.
Overdose symptoms include the following: headache, vomiting, nausea, cyanosis, dizziness.
In case of overdose, symptomatic therapy is necessary.
When treating patients with pathologies of renal function, Streptocide is used with caution. The volume of fluid consumed during the period of treatment should be increased.
With prolonged use, it is recommended to systematically monitor the picture of the blood, liver and kidney function.
Interaction with other drugs
When treating with a drug or an analogue of Streptocide, it is necessary to take into account that novocaine and other drugs with a similar chemical structure, containing a para-aminobenzoic acid residue, may exhibit antisulfanilamide action.
We offer you to read the reviews of people who used the drug Streptocid:
- Victoria. Streptocide is always in my first aid kit. I have two children, they often have abrasions and wounds after playing in the air. Streptocide need to sprinkle wounds so as not to fester. You can also dilute streptocid with water and wipe the walls with mold, perfectly removes.
- Andrew. This is a proven tool. I often go hiking and I like to take this powder with me. It heals well open wounds and disinfects them, which is very important when there is nothing else at hand. But the problem is that finding this drug is not so easy. Half the town run around before you buy. This has become a rarity, surprised, as an excellent remedy.
- Lera. I remember mom as a child, we were treated to our knees first with hydrogen peroxide, then we sprinkled streptocide powder. Vavki healed faster, scars did not leave scary. They say he is now in the form of powder sold. I used to remember in dark bottles, but now they say that in bags. By the way, he didn’t tweak in contact with a wound, which is very important for children. So now I recommend it to everyone).
The structure, active substance and pharmacological action of the following analogues of Streptocide - sulfa drugs:
- Soluble streptocid;
- Sunorphe ointment (contains in addition to sulfanilamide eucalyptus oil, camphor, ephedrine hydrochloride, sulfadimezin, norsulfazol - treats acute and chronic rhinitis).
Before buying an analogue, consult your doctor.
Shelf life and storage conditions
Keep out of reach of children at a temperature not exceeding 25 ° C. The shelf life of liniment - 4 years, powder for external use, ointment and tablets - 5 years.